Brief Report TRANSFUSION MEDICINE No evidence of transmission of chronic lymphocytic leukemia through blood transfusion
نویسندگان
چکیده
Denmark; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Immunology, Naestved Hospital, Naestved, Denmark; Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark; South Danish Transfusion Service/Department of Clinical Immunology, Odense University Hospital, Odense, Denmark; and Hematology Centre, Karolinska University Hospital, Stockholm, Sweden
منابع مشابه
No evidence of transmission of chronic lymphocytic leukemia through blood transfusion.
Monoclonal B-cell lymphocytosis (MBL) is a precursor of chronic lymphocytic leukemia (CLL). Observations of MBL in blood donors raise concern that transmitted MBL may cause recipient CLL. Using a database with health information on 1.5 million donors and 2.1 million recipients, we compared CLL occurrence among 7413 recipients of blood from 796 donors diagnosed with CLL after donation cessation,...
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In this issue of Blood, Hjalgrim et al used the Scandinavian Donations and Transfusions (SCANDAT2) database, which includes comprehensive information on donors and recipients of >20 million blood products handled by the Danish and Swedish blood banks between 1968 and 2010, to address the clinically relevant question of whether chronic lymphocytic leukemia (CLL) is transmitted through blood tran...
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Alterations in the expression of microRNAs (miRNAs) have been proposed to play a role in the pathogenesis of acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL). Dicer is one of the main regulators of miRNA biogenesis, and deregulation of its expression has been indicated as a possible cause of miRNA alterations observed in various cancers. Our aim was to analyze the expre...
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